I am writing this because my friend Evan is in hospice. Repurposed drugs kept him alive with Glioblastoma and quadrupled his survival from 12 months to 48 months, but the standard of care kept his cancer growing.
Evan is my friend and colleague who inspired the writing of my book. And for nearly four years, he was winning the fight against his brain cancer, Glioblastoma, by adding repurposed drugs to the standard treatment. But now, that standard treatment seems to be causing more harm than help. It fueled the regrowth of his cancer.
That is correct. You heard me right.
The standard of care kept his Glioblastoma growing. Evan received this standard treatment not on my advice, but on the advice of a major US Cancer Treatment Center.
Everyone needs to know this. The radiation to his brain and the steroids kept the brain cancer growing. But don’t take my word for it. Listen to the expert, Dr. Thomas Seyfried. And Dr. Paul Marik knows that Dr. Seyfried is correct.
Why is it that this is not common knowledge among Oncologists? Because as Dr. Seyfried has explained, “It is not a good business model [24:00].”
Dr. Seyfried has the answer to cancer in general and Glioblastoma in particular. And the answer has to do with Otto Warburg and his discovery. And it has to do with Hans Krebs and his science. And it has to do with Krebs’ student, Richard Veitche [24:16], with whom Seyfried corresponded.
Cancer remains Big Business in the United States and around the world with expensive and insurance paid Chemotherapy and Radiation.
So, what is the answer to cancer?
Repurposed drugs can help a great deal. They can double, triple or even quadruple survival. I have written extensively about the Care Oncology Clinic’s Four-Drug protocol which helped Evan. But the metabolic therapy can cure. Because cancer is a metabolic, not a genetic disease.
Dr. Seyfried has found the answer. When Watson and Crick discovered the Double Helix Structure of DNA, Seyfried explains that doctors assumed that cancer followed a genetic causation. Forty years later, and after the genome was sequenced, we could not find a common genetic pathway to confirm a genetic cause.
Their scientific explanation is that dysfunctional mitochondria cause cancer. Cancer, according to Warburg and now his successor, Dr. Seyfried, is caused by damaged mitochondria, whereby these damaged mitochondria lose their ability to use oxygen and the Krebs Oxidative Phosphorylation Pathway. These cells then become cancerous and can only ferment to produce energy. They use glycolysis, the fermentation pathway.
The solution becomes simple.
Fermenting cancer cells only can survive by using glucose and in some cases glutamine. Simply consume a diet without glucose, like a calorie-restricted ketogenic diet, and the cancer cells will shrivel and die. However, in certain cancers, like Glioblastoma [GBM], radiation can produce necrosis and that can liberate huge amounts of glutamine, which then can feed the tumor.
In addition, the steroids, commonly used as standard of care in GBM, produce liberal amounts of glucose in the blood, which further fuels the fermenting tumor cells.
As Dr. Seyfried explains, the standard of care in Glioblastoma “seals the death certificate [21:25].”
I look back to my friend and colleague Evan who was given steroids and radiation, and now realize that the therapy itself was his undoing.
Dr. Seyfried explains,
“[01:10:21] Whether it’s in a child or an adult with Glioblastoma, you know they’re finished. You know that the therapy itself is killing those people. And that’s the tragedy. And what I just said to you in that statement that I just made is NOT KNOWN to the majority of practitioners in the field. They are under the impression that this is helping their patient. This is the gap in knowledge that needs to be closed. We cannot continue to do this toxic therapy to these poor people, whether it’s a child or an adult, it speaks to the lack of knowledge on the part of the field treating a disease. IT HAS TO CHANGE. Otherwise, we have to continue seeing these tragedies, one after another. Not only in America, but throughout the world. You’re in Australia. They’re doing the same thing down there as we do here. England, Germany and Japan. They’re all doing the same thing [chemotherapy and radiation and ignoring the real cause, metabolism]. It’s a world-wide tragedy. And it will only change once we come to realize that cancer is a mitochondrial metabolic disease - we could make a dent in this disease so quick if people knew what I just said.”
“We have written a protocol to treat patients with metabolic therapy. It will not be offered in the major centers. It can be offered in the smaller clinics. Guy Tenenbaum talks about his success using this therapy. How compliant are you in not eating carbohydrates? It can be hard for some people.
Dr. Chaffee, a medical doctor, notes that he told a friend of his with GBM about the metabolic therapy, and she remains alive after six years - almost unheard of in GBM [31:22].
Dr. Seyfried explains the glucose-ketone index and what a patient needs to do to achieve success with Glioblastoma. He explains they must keep their glucose-ketone index below 2.0.
Seyfried notes that with the proper motivation and compliance, they can control the growth of their tumor. He notes that patients should never be told there is nothing more that can be done. They must be offered metabolic therapy, even if it does not make Big Pharma or Big Medicine any money.
“[01:17:40] I’ve had people tell me or their loved ones told me that this guy fought the fight. He felt so good about himself. And even though he may not have made it all the way, he lived two or three times longer than he was supposed to live at a much higher quality of life and never had to suffer and die in these painful situations [referring to toxicity from chemotherapy and radiation]. Then there’s many people still fighting the fight, who should have died a long time ago. And they are still on. And if I had the drugs that work with the diet, we would be able to settle this in a much more defined period of time. So yeah, there’s a lot of hope for the future. - I would say the future of cancer is bright - not bleak. It’s a whole new strategy. People are going to emerge in a healthier state and feel much better about themselves.”
Seyfried clarifies what I only wish I had told my friend Evan at the commencement of his GBM treatment,
“[21:20] So it’s the [standard of care] therapies themselves that in other words - it’s bad enough to have a Glioblastoma, it’s even worse to use standard of care to treat it because you’ve more or less signed and sealed the death certificate of this patient. The human brain should rarely if ever be irradiated. This is nonsense. This has to stop. I published a clear paper on how the radiation breaks apart the glutamine-glutamate cycle in the brain freeing up massive amounts of glutamine and the steroids they give these patients increases blood sugar. The two fuels necessary for causing cancer cells to grow out of control are made available in abundant quantities by the very treatments we are doing to these patients. So, we have made no advance in Glioblastoma therapy in almost 100 years. Yet we have a telescope now that orbits one million miles from earth to look at the very origins of our solar system. And yet we do that, yet we’ve made no advance in Glioblastoma. And many other cancers…because the treatments we are using contribute to the demise of these patients. It’s unbelievable.”
So, what is the answer to cancer?
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